Hair analysis and nutritional status

The following paper suggests that the nutritional status of Down Syndrome patients needs special attention. Through hair analysis, an abnormally low level of manganese, calcium and possibly copper in the DS patients was detected.

http://www.ncbi.nlm.nih.gov/pubmed/6456356

DS and epilepsy: a nutritional connection?

Individuals with Down syndrome and individuals with seizures may have lower levels of vitamin A, vitamin B1, folate, vitamin B12, vitamin C, magnesium, manganese, selenium, zinc, carnitine, carnosine, choline, and possibly serine. Excesses of copper, cysteine, phenylalanine, and superoxide dismutase are also sometimes encountered in both disorders. In addition to common nutritional lower levels and excesses, disorders of metabolism involving vitamin B6, vitamin D, calcium, and tryptophan may play a common role.

http://www.ncbi.nlm.nih.gov/pubmed/14729002

Chromosomal disorders and epilepsy

Many chromosomal abnormalities are associated with Central Nervous System (CNS) malformations and other neurological alterations, among which seizures and epilepsy. Some of these show a peculiar epileptic and EEG pattern. Epileptic syndromes are frequently reported in chromosomal disorders.

Also see Epilepsy